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Photo: The Canadian Press. All rights reserved.

Authorities say a loud explosion has leveled a home in Indianapolis and set four others ablaze in a neighborhood, causing several injuries. Capt. Rita Burris with the Indiana Fire Department told The Associated Press that firefighters are still working to put out the flames after the explosion around 11 p.m. Saturday Nov. 10, 2012. (AP Photo/The Indianapolis Star, Matt Kryger)

A deafening explosion that leveled two homes and set two others ablaze forced about 200 people from a devastated Indianapolis neighbourhood overnight.

Authorities said one body was recovered after the flames were extinguished from the blast that shattered windows, crumpled walls and did other damage to dozens of other homes.

Two people were taken to a hospital with minor injuries, said Lieut. Bonnie Hensley, with the Indianapolis Fire Department. But she cautioned authorities were going through the rubble and conducting a house-by-house search for anyone else in the hours before dawn.

"This looks like a war zone; it really does," Hensley told The Associated Press. "Police officers and fire department officials remain at the scene searching for other possible victims. They've brought in search lights as they look through the ruined homes."

She declined to identify the only confirmed fatality, saying only that the body was found in one of the levelled homes.

The explosion at 11 p.m. Saturday destroyed two houses that were side by side and spread fire to two other nearby homes in the neighbourhood on the south side of the city, she said. The blast was heard for miles all around.

She added that at least two dozen other homes on blocks all around were damaged by flying debris as well as from the shock wave from the blast.

Many people were asleep at the time and had to be evacuated in pyjamas, scooping up their pets as they left hastily, authorities said. They left what some described as a chaotic scene of tall flames rising on the Indianapolis skyline.

Survivors reported shattered windows, caved-in walls and garage doors knocked off their hinges. And of the two homes that were leveled by the blast, Hensley said: "There's nothing left."

Complicating the pre-dawn search of the neighbourhood, authorities did not know definitively how many people were in the neighbourhood when the blast occurred. "People scattered when all this happened, so we're not really sure how many people we're looking for," Hensley said.

Bryan and Trina McClellan were at home with their 23-year-old son Eric when the shock wave from the blast a block away shuddered through their home. It knocked the windows out along one side of their home and their first instinct was to check on their two toddler grandchildren in the basement. One was holding his ears and saying "Loud noise, loud noise."

Eric McClellan said he ran to the scene of the explosion.

"Somebody was trapped inside one of the houses and the firefighters were trying to get to him. I don't know if he survived," he said.

He said he didn't know the man's fate as firefighters ordered him to leave.

The cause of the explosions remains unknown, authorities said. Investigators were expected to better assess the rubble after daybreak for clues to what happened. Meanwhile, all power, gas and other utilities were shut off as a precaution as emergency officials swarmed the site.